Senior Director Clinical Biomarkers, BioPharma Business Development

The Senior Director Clinical Biomarkers, BioPharma Business Development will provide strategic,

scientific, and organizational leadership across a broad oncology diagnostics portfolio. This

executive will be responsible for defining and advancing biomarker and translational medicine

strategies across early- and late-stage BioPharma collaborations in support of Natera’s strategic

goals eg TOMR and surrogacy in collaboration with Natera’s lifecycle and clinical development

teams.

 

The ideal candidate will bring deep expertise in oncology drug development, biomarker

strategy, and translational research, with experience spanning Phase 1–3 studies and multiple

therapeutic modalities, including immunotherapy, targeted therapy, and antibody-drug

conjugates.

 

Key Responsibilities

 Lead translational medicine and clinical biomarker strategy across oncology programs

within and beyond the BioPharma BD portfolio.

 Define and oversee biomarker plans supporting late-stage development in solid tumors

within the BioPharma space (Pharma Lab Services, BD partnerships) including assay

strategy, translational endpoints, data generation, data interpretation, publication

planning, and regulatory filing support.

 Partner closely with clinical development, bioinformatics, medical affairs, regulatory,

diagnostics, and commercial teams to ensure assay development portfolio and

biomarker strategies are aligned with overall BioPharma BD needs.

 Work with external partners on their Natera-supported translational research efforts to

help them leverage Natera capabilities to optimize the value of their projects: these may

include identifying novel targets, characterizing resistance mechanisms, developing

novel predictive biomarkers and next-generation clinical tools, including blood-based

biomarkers, digital pathology, radiomics, and AI/ML-enabled approaches.

 Support development and lifecycle strategies that enable successful product

differentiation, launch readiness, reimbursement, and broader clinical adoption.

 

BioPharma Deliverables

 Contribute to study design and evidence-generation plans that support our BioPharma

efforts across BD, Pharma Lab Services, and internal R&D.

 Work with the RWD, AI, and bioinformatics teams to develop use cases for existing data

and build out new concepts for new data types as they are created.

 Apply translational insights to inform patient selection, development decisions, and

clinical differentiation strategies for our customers.

 

External Relationships & Strategic Engagement

 Establish and lead strategic collaborations with BioPharma partners, academic

institutions, cooperative groups, scientific consortia, and key opinion leaders.

 Represent the company in external scientific and clinical initiatives that shape the future

of biomarker-enabled oncology development.

 Build productive external partnerships that accelerate innovation, evidence generation,

and adoption of novel translational approaches.

 

External Scientific Presence

 Serve as a visible scientific leader through publications, invited presentations, advisory

participation, and broader thought leadership in oncology and precision medicine.

 Maintain strong credibility in the external scientific community, with the ability to

engage effectively with academic leaders, consortia, and industry partners.

 Contribute to the company’s scientific reputation through high-impact external

presence and publication strategy.

 

Preferred Qualifications

 Advanced degree in a relevant scientific discipline; PhD, MD, DVM, or equivalent

strongly preferred.

 15+ years of relevant experience in translational medicine, clinical biomarker

development, oncology drug development, or related fields.

 Significant experience in biomarker-driven clinical development and medical affairs

across early- and late-stage oncology programs.

 Demonstrated success in building external scientific relationships and representing

organizations in high-profile external settings.

 Strong record of scientific leadership, cross-functional collaboration, and strategic

execution.

The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.Remote USA$248,100—$310,100 USD

Compensation & Total Rewards 

This range reflects a good-faith estimate of the base pay we reasonably expect to offer at the time of  hire. Final compensation will vary based on experience, qualifications, and internal equity considerations.

This position is also eligible for additional compensation and benefits through Natera’s robust Total Rewards program, including:

• Annual performance incentive bonus

• Long-term equity awards

• Comprehensive health benefits (medical, dental, vision)

• 401(k) with company match

• Generous paid time off and company holidays

• Additional wellness and work-life benefits

Compensation Range $248,100—$310,100 USD

OUR OPPORTUNITY

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

WHAT WE OFFER

Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!

For more information, visit www.natera.com.

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.

All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.

If you are based in California, we encourage you to read this important information for California residents. 

Link: https://www.natera.com/notice-of-data-collection-california-residents/

Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.

For more information:
- BBB announcement on job scams 
- FBI Cyber Crime resource page