Clinical Trial Manager or Sr Clinical Trial Manager

All Jobs  >  Clinical Trial Manager or Sr Clinical Trial Manager Bridge Bio Oncology Therapeutics Apply Clinical Trial Manager or Sr Clinical Trial Manager Fully Remote • Nationwide Apply Job Type Full-time Description   About BridgeBio Oncology TherapeuticsBBOT is a clinical-stage biopharmaceutical company advancing a next-generation pipeline of novel small molecule therapeutics targeting RAS and PI3K malignancies. BBOT has the goal of improving outcomes for patients with cancers driven by the two most prevalent oncogenes in human tumors. For more information visit BBOTx.com.Who You AreWe are seeking a Clinical Trial Manager (CTM) or Senior Clinical Trial Manager (Sr. CTM) (Sr. CTM) to support the execution of BBOT’s clinical trials across all phases, with a focus on early-phase oncology. Reporting to the Director of Clinical Operations, the Sr. CTM will play a critical role in supporting cross-functional planning, day-to-day oversight of trial activities, and ensuring the delivery of high-quality, timely clinical data. The Sr. CTM will work closely with internal and external partners, including CROs, vendors, and clinical sites. Global trial experience a plus. ResponsibilitiesSupport the Director in overseeing global clinical trial execution, including site activation, enrollment, monitoring, and closeoutSupport the Director in leading      cross functional trial team meetings and ensure alignment on key deliverables, timelines, and risk mitigation strategies. Manage day-to-day operational activities for assigned studies, ensuring adherence to timelines, budgets,  and quality standardsDrive vendor integration strategies to ensure seamless execution between CRO, central labs, and any specialty service providers. Act as the main clinical operations point of contact for assigned study-level tasks, including managing CROs and vendors in collaboration with the DirectorEnsure completeness and inspection-readiness of the trial master file (TMF/eTMF) Support the development and maintenance of key operational documents including study manuals, ICFs, tracking tools, and monitoring plansParticipates in the conduct of audits and support regulatory inspections related to GCPMonitor regulatory and GCP compliance across trial activities and support audit/inspection readinessReview clinical trial data listings to support identification and resolution of protocol deviations, data trends, and outstanding queriesOwn CRO and vendor oversight by      tracking deliverables, proactively identifying risks until issue resolution, and performance metrics in partnership with the Program/Study LeadOversee lab sample management processes, including sample tracking, shipment, reconciliation, and vendor coordination to ensure timely and compliant handling of biological specimensContributes to continuous  process improvement and SOP development Participate in team meetings, providing clinical operations insights and updates to internal stakeholdersAdditional Responsibilities (Sr. CTM only)Lead cross-functional trial team meetings and drive alignment on key deliverables, timelines, and risk mitigation strategies with minimal oversightServe as primary clinical operations lead for assigned programs, representing the function in governance and leadership meetingsProvide strategic input into study design, operational feasibility, and protocol development in collaboration with cross-functional teamsLead SOP development and drive continuous improvement initiatives across clinical operationsMentor and develop CTMs and junior team members to build internal operational capabilities and a high-performing team culture Requirements   Education and Qualifications – Clinical Trial Manager (CTM) Bachelor’s degree in life sciences or related fieldMinimum 4 years of experience in Clinical Operations, working with CROs and other vendorsStrong understanding of CRO/vendor oversight and clinical...