Histotech Assistant - Histology

Rochester, MNFull-timePosted Jun 26, 2026

As a Histotech Assistant working in the Histology Laboratory, you will be responsible for contributing to diagnosis, treatment, and care of patients by performing a volume and variety of Histopathology technical procedures as trained under direct supervision including embedding of tissue blocks and performing microtomy.

 Additional responsibilities include: 

  • Retrieval and verification of patient samples
  • Tracking specimens
  • Accessioning
  • Specimen photography
  • Processing tissue specimens using various protocols
  • Maintaining laboratory equipment
  • Performing Hematoxylin and Eosin staining
  • Performing coverslipping techniques
  • Performing case assembly and distribution
  • Handling outside/consultation material
  • Troubleshooting equipment, reagent, and case issues
  • Reagent preparation
  • Reviewing pending list/logs
  • Filing and retrieving tissue blocks and slides
  • Handling/disposal of hazardous chemicals
  • Subject matter expert of Lab Information System
  • Record retention
  • Answering phones

Visit the Clinical Labs career site to watch a brief video of Olyvia discussing her role as a Histotech Assistant at Mayo Clinic. 

*This position does not typically meet ASCP Board of Certification Route 2 eligibility requirements for Histology Technician Examination. 

*Individuals hired to this position are required to complete 2 years in this position before becoming eligible to apply to other positions within Mayo Clinic.

**This position is not eligible for visa sponsorship; Also, Mayo Clinic DOES NOT participate in the F-1 STEM OPT extension program. 

To be considered for this position, you must have an associate's degree. In lieu of an associate degree, you may be considered if you have a high school diploma or GED and 2 years of relevant/demonstrated experience.

*This is a limited tenure position for a maximum of 3 years. You will be eligible to reduce to 0.5 full-time equivalency (FTE) if accepted into the Mayo Clinic School of Health Sciences (MCSHS) Histology Technician Program. You must work towards completion of MCSHS Histology Technician program prerequisites:  https://college.mayo.edu/academics/health-sciences-education/histology-technician-program-arizona-florida-and-minnesota/.

Additional Requirements

  • Medical terminology preferred. 
  • Laboratory or leadership experience preferred. 
  • Demonstrated communication, organizational, and problem-solving skills. 

 

Application Requirements

*All must be included for your application to be considered

  • CV/Resume
  • Cover letter
  • NACES detailed international equivalency for foreign degrees.  
  • Internal candidates must provide their past three performance appraisals. 

**DLMP employees that have been in current lab/position for less than 2 years must attach early release approval from supervisor. 

***Non-DLMP internal applicants that have been in their current department/position for less than 1 year must attach early release approval from supervisor. 

*International transcript:

  • MUST have a DETAILED equivalency evaluation.
  • MUST show US equivalent degree.

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