Director, Total Rewards & Operations
South San Francisco, CAPeople Manager$240kPosted Jul 10, 2026
Director, Total Rewards & OperationsRemotePeople and CultureFull timeLRP-2026-020United StatesShare this job DescriptionEncoded Therapeutics Inc. is a biotechnology company advancing precision medicines for a broad range of genetic disorders. Our mission is to unlock new opportunities for viral gene therapy through genomics-driven discovery. We focus on delivering life-changing advances for individuals with genetic disorders not addressable with current approaches. For more information, please visit www.Encoded.com.Encoded is seeking a Director, Total Rewards & Operations. This is a build role at a pivotal stage of company growth. As Encoded scales, the People function must mature its compensation and equity programs, modernize its HR systems and operations, and establish the robust data integrity and compliance frameworks required of an expanding, multi-site organization. The Director, Total Rewards & Operations will own that build.This is a build role at a pivotal stage of company growth. As Encoded scales, the People function must mature its compensation and equity programs, modernize its HR systems and operations, and establish the robust data integrity and compliance frameworks required of an expanding, multi-site organization. The Director, Total Rewards & Operations will own that build.This is not a maintain-the-status-quo seat. The right person is a total rewards practitioner with real compensation design depth who also has the operational instinct to architect systems, lead vendor relationships and transitions, and stand up scalable controls and compliance rigor. They will be a key partner to Finance, Legal, and the People & Culture leadership team, and a credible counterpart to our external compensation consultants, brokers, and auditors.The defining feature of this role is build and scale - evolving Encoded's compensation, equity, and HR-operations infrastructure, including its HR technology and service-delivery model, to support the company's growth and increasing organizational maturity.RequirementsTotal RewardsPartner with the VP, People & Culture and the Board's Compensation Committee to design and implement scalable, market-competitive executive and broad-based incentive structures appropriate to a maturing organization.Partner with Finance on the design and market-competitiveness of the equity program - including grant guidelines, benchmarking grant levels against market, and the evaluation of future equity vehicles (e.g., an ESPP).Own compensation benchmarking and market analysis, including Radford survey submissions and the maintenance of job architecture, salary structures, and pay bands.Run the total rewards calendar end to end - merit and bonus planning, mid-year and year-end compensation cycles, and the compensation components of the performance process.Serve as the subject-matter expert on pay equity, compensation philosophy, and total rewards communications to managers and employees.HR Operations, Systems & ComplianceLead the evolution of Encoded's HR operations and service-delivery model, including assessing and, where appropriate, transitioning HR technology, payroll, and benefits delivery to support the company's scale.Own the HR technology roadmap and serve as system owner for the HR tech stack, with a focus on integration across HRIS, payroll, benefits, and downstream systems.Own vendor management for key People partnerships - benefits brokers, leave-of-absence providers, HRIS and payroll vendors, and compensation survey providers - including selection, contracting, and performance management.Oversee the annual operational compliance cycle, including 401(k) plan audit, ACA reporting, Section 125 / FSA non-discrimination testing, and EEO-1 reporting.In partnership with Finance, build and maintain internal controls and data integrity over HR and payroll data that meet the standards of a maturing, audit-ready organization, and ensure data integrity through audit cycles.Develop and maintain readiness...