Senior Associate Scientist, LC/LC-MS

Career Areas Career Stories Join Talent Community Candidate Login English English Italiano Español Français Português Norsk Deutsch 日本語 Bahasa melayu 中文 (简体) 中文 (繁體) 한국어 ภาษาไทย Nederlands Polski Yкраїнська Hrvatski Ελληνικά Magyar čeština Türkçe Pусский Haitian עברית Brazilian Português Dansk Suomi Svenska Français (Canada) Português (Portugal) Careers Home Life at BMS Career Areas Student Opportunities Events How We Recruit Career Stories Search this site Join Talent Community Candidate Login English English Italiano Español Français Português Norsk Deutsch 日本語 Bahasa melayu 中文 (简体) 中文 (繁體) 한국어 ภาษาไทย Nederlands Polski Yкраїнська Hrvatski Ελληνικά Magyar čeština Türkçe Pусский Haitian עברית Brazilian Português Dansk Suomi Svenska Français (Canada) Português (Portugal) Single PositionView All JobsSenior Associate Scientist, LC/LC-MSCambridge - MA - US No longer accepting applications.Job IDR1603879Date posted06/25/2026DepartmentCell TherapyPosition Summary: BMS at Kendall Square is seeking a highly skilled and motivated Senior Associate Scientist with strong expertise in analytical method development to support the advancement of novel RNA therapeutics. The successful candidate will leverage liquid chromatography and LC/MS technologies to design, develop, and execute analytical methods that enable comprehensive characterization of lipids, antibodies, and RNA-based modalities across discovery and development stages. This role will play a critical part in generating high-quality analytical data to support product understanding, process development, and CMC strategies.Responsibilities: Independently design, develop, and optimize analytical methods to characterize RNA-based therapeutics, lipid nanoparticles, and related components using advanced LC and LC/MS platforms.Lead phase-appropriate method lifecycle activities, including method development, qualification, validation, and transfer to internal and external laboratories (e.g., CROs/CDMOs), with authorship of SOPs, protocols, and technical reports.Collaborate cross-functionally with process development, formulation, research, and manufacturing teams to support analytical development, troubleshoot issues, and enable program milestones and timelines.Troubleshoot complex analytical challenges, interpret data, and provide scientifically sound recommendations to resolve issues and improve assay performance and robustness.Perform and oversee routine and non-routine analytical testing, including data review, verification, and interpretation to ensure data quality, integrity, and compliance with internal standards.Operate, maintain, and troubleshoot LC and MS instrumentation.Analyze and communicate complex analytical data, generating clear, concise reports and presentations to inform technical teams and leadership decisionsQualifications: B.S./M.S. in Analytical Chemistry, Biochemistry, or a related discipline with 2+ years of relevant CMC-related experience; PhD. candidates with the appropriate experience will be considered.Experience with LC-MS method development, impurity characterization, and structural elucidation using high-resolution MS platforms.Experience with LNP drug products, antibodies, and RNA/oligonucleotide analysis preferred.Ability to manage multiple projects and priorities in a fast-paced environmentStrong technical writing skills for reports, protocols, and regulatory documentationFamiliarity with regulatory expectations (e.g., ICH, FDA) for analytical data and submissionsPosition Summary: BMS at Kendall Square is seeking a highly skilled and motivated Senior Associate Scientist with strong expertise in analytical method development to support the advancement of novel RNA therapeutics. The successful candidate will leverage liquid chromatography and LC/MS technologies to design, develop, and execute analytical methods that enable comprehensive characterization of lipids, antibodies, and RNA-based modalities across discovery and development stages. This role will...