Sr. Manager, Sample Management

Skip to main content Sr. Manager, Sample Management Tyra Biosciences Carlsbad, CA Apply Sr. Manager, Sample Management Tyra Biosciences Carlsbad, CA 1 week ago 184 applicants See who Tyra Biosciences has hired for this role Apply Save Report this job Tyra Biosciences, Inc. is seeking a Sr. Manager, Sample Management that is a highly organized and scientifically driven professional to lead and support clinical sample management for small-molecule drug development programs.The Sr. Manager, Sample Management will be responsible for ensuring high-quality sample collection, processing, storage, shipment, reconciliation, archival, and final disposition of PK, PD, and biomarker samples for multiple programs and across global trials. This individual will also assist with vendor oversight, analysis plans, as well as data integrity checks and data transfer logistics. The candidate will be an integral member of study teams and will ensure sample management compliance with study protocols and quality standards (e.g., ICH GCP guidelines). The ideal candidate will bring strong technical expertise, attention to detail, and the ability to operate effectively in dynamic environments.Job ResponsibilitiesPlans, coordinates and oversee all operational activities for the collection, handling, shipment, storage, and delivery of biomarkers, pharmacogenetics, and pharmacokinetic samples within Phase I to III clinical trials, while being simultaneously assigned to multiple global trials.Develop Study Sample Management Plans to document cross-functional agreements on the lifecycle and reconciliation plan for each sample type.Maintain vendor relationships and readiness through regular interactions, correspondence, and site visits (where appropriate).Maintain accurate records of all sample-related activities, including deviations and corrective actions.Provide input for sample collections in key documents such as clinical study protocols/synopses, lab manuals, and informed consent forms to ensure the logistical feasibility of the sample collection strategy.Participate in vendor selection, management and oversight, and assist with budget, quotes, purchase order, and invoice tracking/approval.Train study team members and investigational site personnel in biosample handling requirements.Supports the study team with the submission to IRBs and ECs and responds to IRB/EC requests.Accountable for ensuring that the data received is consistent with the collection and assay plans and protocol.Report on status including reconciliation against consent.Ensure sample management records are always inspection-readyBuild relationships and foster excellent collaboration and communication with internal and external stakeholders and partnersContributes to process improvement initiatives when requiredMinimum RequirementsBachelor’s degree in life sciences with a minimum of >5 years of pharmaceutical/biotech industry experience, specifically in clinical sample management and oversightSound understanding of clinical samples and their life cycle management is essentialKnowledge of regulatory guidelines (e.g., ICH-GCP)Proven ability to communicate and collaborate effectively within and across teamsSelf-motivated team player who works effectively in a fast-paced environment to meet deadlines, with a can-do attitude and persistent attention to detailExcellent communication, influencing, collaboration, organizational, and...